Gearbox is apparently aware of the problem and is working on a fix. A post on their message board states, "Unfortunately there isn't a fix just yet, but when one is available we hope to be able to repair as much of your character data as possible." In the meantime we would suggest just playing the game in single player if you don't want to risk losing your character progression.
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123456Posted at 11:00AM on Dec 2nd 2009 by kaplann